Immunotherapy has revolutionized cancer treatment and led to a significant increase in patient survival rates and quality of life.However, the effectiveness of current immunotherapies is limited by various factors, including immune evasion mechanisms and serious side effects.Hydrogels are a type of medical material with an ideal biocompatibility, v
We describe an unusual case of stroke manifesting as alien hand syndrome (AHS) causing sudden onset of rme ufx iii abnormal hand movements.The patient reported his left arm would move outside his control and grab things in his surroundings without his conscious will.He felt his arm did not belong to him.Examination showed left arm brisk reflexes, a
The present study was designed to investigate the role of Schwann cell (SC) Piezo1 in peripheral nociception.We first developed an AAV vector that has primary SC tropism after delivery into the sciatic (or tibial) nerve.This was achieved by packing AAV-GFP transcribed by a CBA promoter using a capsid AAVolig001 to generate AAVolig001-CBA-GFP.Six we
Digital twins are virtual models of physical artefacts that may or may not be synchronously connected, and that can be used to simulate their behavior.They are widely used in several domains such as manufacturing and automotive to enable achieving specific quality goals.In the health domain, so-called digital patient twins have been understood as v